Frontline vs Advantix – Which is Better?

Frontline Vs AdvantixTicks and fleas are a complete nuisance for dogs not to mention dangerous to their health. If you are like me you’ll want to protect your dog using only the best flea and tick control medication. Frontline Plus and Advantix II are two of the top medications for preventing and controlling fleas. This article compares Frontline vs. Advantix to help you buy the best option for your dog.

Frontline vs Advantix Comparison Chart

The chart below compares Frontline and Advantix features and effectiveness. We used 13 benchmarks that are important in evaluating the two medications.

Feature Frontline Plus K9 Advantix II
Waterproof Yes Yes
Repels & Kills Sand Flies No Yes
Repels Biting & Stable Flies No Yes
Repels & Kills Mosquitoes No Yes
Kills Lice Yes Yes
Kills Flea Eggs & Larvae Yes Yes
Repels Ticks No Yes
Kills Ticks Yes Yes
Repels Fleas No Yes
Kills Fleas Yes Yes
Rx Prescription Required ​No No
Active Ingredient(s) Fipronil/(S)-Methoprene Permethrin/Pyriproxyfen/Imidacloprid
Duration to take effect Kills Ticks within 48 hours
Kills Fleas within 12 hours
Kills Fleas within 12 hours
Price Check Price Check Price

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